The Apothecary Diaries Season 2 has achieved something remarkable: with an 8.91/10 rating on MyAnimeList, it became 2025's highest-rated anime television series and the 20th best-rated anime of all time. Let's explore why this series has resonated so deeply with audiences.
The Perfect Blend
At its core, The Apothecary Diaries succeeds because it refuses to be pigeonholed. It's part historical drama, part medical mystery, part romance, and part court intrigue. Maomao's adventures in the imperial palace keep viewers guessing while developing meaningful character relationships.
A Protagonist for the Ages
Maomao stands out as one of the most refreshing protagonists in recent anime history. Her obsession with poisons and medicine, combined with her sharp wit and refusal to play political games, makes her instantly compelling. She's capable without being overpowered, clever without being insufferable.
Production Excellence
TOHO animation studio delivered consistently beautiful animation throughout the season. The attention to historical detail, from costume design to court etiquette, demonstrates remarkable research and care.
Universal Appeal
Perhaps most importantly, The Apothecary Diaries has transcended typical anime demographics. Its intelligent writing, minimal fanservice, and focus on mystery-solving have attracted viewers who might not typically watch anime, expanding the medium's reach.
